By combining high-resolution observations from JWST and HST, we have measured the stellar masses, star formation rates (SFRs), and multi- wavelength morphologies of galaxies in the CANDELS fields. Furthermore, based on rest-frame 1um morphologies, we have derived spatially resolved stellar mass and SFR surface density (Sigma_*_ and Sigma_SFR_) profiles for 46313 galaxies with reliable structural measurements at 0<z<4 and log(M*/M_{sun}_)>8, and provide the corresponding catalogue. For star-forming galaxies (SFGs), our results show excellent consistency with previous studies in terms of the star formation main sequence and the size-mass relation, demonstrating the robustness of our stellar mass and SFR measurements. For spatially resolved profiles, we find that at higher redshifts (z>2.5), the median radial profile of Sigma_SFR_ is nearly parallel to but slightly steeper than that of Sigma_*_. This results in mildly negative gradients in the specific SFR (sSFR) profiles across all stellar mass bins considered. These findings indicate that galaxies at z>2.5 cannot grow in size via only in-situ star formation, challenging the understanding of galaxy size evolution beyond the cosmic noon. In contrast, at z<2.0, the sSFR profiles transition to exhibit more and more positive gradients at lower redshifts, consistent with an inside-out growth scenario where star formation preferentially expands the galactic outskirts.