Filamentary structures are common morphological features of the cold, molecular interstellar medium (ISM). Recent studies have discovered massive, hundred-parsec-scale filaments that may be connected to the large-scale, Galactic spiral arm structure. Addressing the nature of these giant molecular filaments (GMFs) requires a census of their occurrence and properties. We perform a systematic search of GMFs in the fourth Galactic quadrant and determine their basic physical properties. We perform a systematic search of GMFs in the fourth Galactic quadrant and determine their basic physical properties. Methods. We identify GMFs based on their dust extinction signatures in the near- and mid-infrared and the velocity structure probed by ^13^CO line emission. We use the ^13^CO line emission and ATLASGAL dust emission data to estimate the total and dense gas masses of the GMFs. We combine our sample with an earlier sample from literature and study the Galactic environment of the GMFs.