We present the South Galactic Pole (SGP) data release from the GaLactic and Extragalactic All-sky Murchison Widefield Array (GLEAM) survey. These data combine both years of GLEAM observations at 72-231MHz conducted with the Murchison Widefield Array (MWA) and cover an area of 5,113 deg^2^ centred on the SGP at 20h40m<RA<05h04m and -48{deg}<Dec<-2{deg}. At 216MHz, the typical rms noise is ~5mJy/beam and the angular resolution ~2 arcmin. The source catalogue contains a total of 108851 components above 5{sigma}, of which 77 per cent have measured spectral indices between 72 and 231MHz. Improvements to the data reduction in this release include the use of the GLEAM Extragalactic catalogue as a sky model to calibrate the data, a more efficient and automated algorithm to deconvolve the snapshot images, and a more accurate primary beam model to correct the flux scale. This data release enables more sensitive large-scale studies of extragalactic source populations as well as spectral variability studies on a one-year timescale.