We present speckle interferometric measurements of binary stars performed during August of 2010 with the 1.5m telescope and during November of 2010 with the 2.1m telescope of the Observatorio Astronomico Nacional at SPM (Mexico). We report here the results of 238 measurements of 225 pairs with a primary limiting magnitude of V=12.2; 211 of them have separations less than 1". The mean error in separation is 0.03" and 1.5{deg} in position angle. Some of the position angles were determined with the usual 180{deg} ambiguity.