In this paper, we present results from long-term V(RI)c photometric observations of the pre-main-sequence stars V2764 Ori and LkHa 301, located in the field of the McNeil's Nebula within the Orion star-forming complex. Our observations were performed in the period from August 2004 to November 2021 with three telescopes and seven different types of CCD cameras. Photometric observations, especially concerning the long-term behavior of the stars, are missing in the literature. We present the first photometric monitoring covering 17 years. Our data indicate that the variability of both stars is typical for classical T Tauri stars.