Photoelectric observations of HD 51585 (OY Gem), a B[e] star with an infrared excess and a candidate for protoplanetary nebulae, obtained with a 60-cm telescope at the Crimean Station of Sternberg Astronomical Institute in 1992-2005 are presented. The star exhibited rapid irregular brightness variations with amplitudes from 0.1mag in the V band to 0.2mag in the U band within the observing season as well as slow systematic variations. with a quasi-period of ~2800-days. Low-resolution spectroscopy performed in 1994-2005 has revealed significant variability of the Balmer and Paschen hydrogen emission lines as well as the HeI and OI lines. Equivalent widths are given for the HI, HeI, OI, and FeII lines. Correlation has been found between the star's photometric variability and the hydrogen line intensities.