We analyse Spitzer Multiband Imaging Photometer (MIPS) 24um observations, and Sloan Digital Sky Survey Data Release 7 optical broad-band photometry and spectra, to investigate the star formation (SF) properties of galaxies residing in the Coma supercluster region. We find that SF in dwarf galaxies is quenched only in the high-density environment at the centre of clusters and groups, but that passively evolving massive galaxies are found in all environments, indicating that massive galaxies can become passive via internal processes. The SF-density relation observed for the massive galaxies is weaker relative to the dwarfs, but both show a trend for the fraction of star-forming galaxies (f_SF_) declining to ~0 in the cluster cores. We find that active galactic nucleus activity is also suppressed among massive galaxies residing in the cluster cores.