We present an enhanced version of the publicly available Stripe 82X catalog (S82-XL), featuring a comprehensive set of 22737 unique X-ray point sources identified with a significance >~4{sigma}. This catalog is four times larger than the original Stripe 82X catalog, by including additional archival data from the Chandra and XMM-Newton telescopes. Now covering ~54.8deg^2^ of nonoverlapping sky area, the S82-XL catalog roughly doubles the area and depth of the original catalog, with limiting fluxes (half-area fluxes) of 3.4x10^-16^ (2.4x10^-15^), 2.9x10^-15^ (1.5x10^-14^), and 1.4x10^-15^ (9.5x10^-15^)erg/s/cm2 across the soft (0.5-2keV), hard (2-10keV), and full (0.5-10keV) bands, respectively. S82-XL occupies a unique region of flux-area parameter space compared to other X-ray surveys, identifying sources with rest-frame luminosities from 1.2x10^38^ to 1.6x10^47^erg/s in the 2-10keV band (median X-ray luminosity, 7.2x10^43^erg/s), and spectroscopic redshifts up to z~6. By using hardness ratios, we derived the obscuration of active galactic nuclei (AGNs), obtaining a median value of log(N_H_/cm^2^)=21.6_-1.6_^+1.0^ and an overall, obscured fraction (log(N_H_/cm^-2^)>22) of ~36.9%. S82-XL serves as a benchmark in X-ray surveys and, with its extensive multiwavelength data, is especially valuable for comprehensive studies of luminous AGNs.