We observationally investigate star formation process occurring in AFGL 5157 (area ~13.5pcx13.5pc) using a multi-wavelength approach. Embedded filaments are seen in the Herschel column density map, and one of them is identified as an elongated filamentary feature (FF) (length ~8.3pc; mass ~1170M_{sun}_). Five Herschel clumps (M_clump_~45-300M_{sun}_) are traced in the central part of the FF, where an extended temperature structure (T_d_~13.5-26.5K) is observed. In the direction of the central part of the FF, the warmer region at T_d_~20-26.5K spatially coincides with a mid-infrared shell surrounding a previously known evolved infrared cluster. Diffuse H{alpha} emission is traced inside the infrared shell, suggesting the presence of massive stars in the evolved cluster. Based on the surface density analysis of young stellar objects (YSOs), embedded clusters of YSOs are traced toward the central part of the FF, and are distributed around the infrared shell. Previously detected H_2_O masers, H_2_ knots, massive protostar candidates, and an H II region are also seen toward the embedded clusters. Using the ^12^CO and ^13^CO line data, the central part of the FF is observed at the overlapping zones of two filamentary molecular clouds (length ~12.5pc) around -20 and -17km/s, which are also connected in velocity. Our observational results suggest that the formation of massive stars appears to be triggered by a collision of two filamentary molecular clouds, which might have also influenced the birth of YSOs in AFGL 5157.