I present integrated colors and surface brightness fluctuation magnitudes in the mid-infrared (IR), derived from stellar population synthesis models that include the effects of the dusty envelopes around thermally pulsing asymptotic giant branch (TP-AGB) stars. The models are based on the Bruzual & Charlot CB* isochrones; they are single-burst, range in age from a few Myr to 14Gyr, and comprise metallicities between Z=0.0001 and Z=0.04. I compare these models to mid-IR data of AGB stars and star clusters in the Magellanic Clouds, and study the effects of varying self-consistently the mass-loss rate, the stellar parameters, and the output spectra of the stars plus their dusty envelopes. I find that models with a higher than fiducial mass-loss rate are needed to fit the mid-IR colors of "extreme" single AGB stars in the Large Magellanic Cloud. Surface brightness fluctuation magnitudes are quite sensitive to metallicity for 4.5{mu}m and longer wavelengths at all stellar population ages, and powerful diagnostics of mass-loss rate in the TP-AGB for intermediate-age populations, between 100Myr and 2-3Gyr.