We have detected 506 i-dropouts (z~6 galaxies) in deep, wide-area HST ACS fields: HUDF, enhanced GOODS, and HUDF parallel ACS fields (HUDF-Ps). The contamination levels are <~8% (i.e., >~92% are at z~6). With these samples, we present the most comprehensive, quantitative analyses of z~6 galaxies yet and provide optimal measures of the UV luminosity function (LF) and luminosity density at z~6, and their evolution to z~3. We redetermine the size and color evolution from z~6 to z~3. Field-to-field variations (cosmic variance), completeness, flux, and contamination corrections are modeled systematically and quantitatively.