We present a comprehensive analysis of young stellar object (YSO) variability within the M17 Southwest Extension (M17 SWex), using 3.5yr of monitoring data from the James Clerk Maxwell Telescope (JCMT) Transient Survey at submillimeter and 9yr from the NEOWISE mission at mid-infrared (mid-IR). Our study encompasses observations of 147 bright submillimeter peaks identified within our deep JCMT coadded map as well as 156 YSOs in NEOWISE W1 and 179 in W2 that were previously identified in Spitzer surveys. We find three robust submillimeter variables: two are candidate YSOs and one is a likely extragalactic source. At mid-IR wavelengths, our analysis reveals secular and stochastic variability in 47 YSOs, with the highest fraction of secular variability occurring at the earliest evolutionary stage. This is similar to what has previously been observed for low-mass YSO variability within the Gould Belt. However, we observe less overall variability in M17 SWex at both the submillimeter and mid-IR. We suspect that this lower fraction is due to the greater distance to M17 SWex. Our findings showcase the utility of multiwavelength observations to better capture the complex variability phenomena inherent to star formation processes and demonstrate the importance of years-long monitoring of a diverse selection of star-forming environments.