We present an extensive time-series radial-velocity (RV) survey of stars in the rich open cluster NGC7789 (1.6Gyr, [Fe/H]=+0.02). The stellar sample lies within an 18' circular radius from the cluster center (10pc in projection, or about 2core radii), and includes giants, red clump stars, blue stragglers, red stragglers, sub-subgiants, and main-sequence stars down to 1mag below the turnoff. Our survey began in 2005 and comprises more than 9000 RV measurements from the Hydra Multi-Object Spectrograph on the WIYN 3.5m telescope. We identify 624 likely cluster members and present the orbital solutions for 81 cluster binary stars with periods between 1.45 and 4200days. From the main-sequence binary solutions we fit a circularization period of 7.2_-1.1_^+0.6^days. We calculate an incompleteness-corrected main- sequence binary frequency of 31%{+/-}4% for binaries with periods less than 104days, similar to other WIYN Open Cluster Survey (WOCS) open clusters of all ages. We detect a blue straggler binary frequency of 33%{+/-}17%, consistent with the similarly aged open cluster NGC6819. We also find one secure, rapidly rotating sub-subgiant and one red straggler candidate in our sample.