We present an analysis of J, H, and Ks time-series photometry obtained with the southern 2MASS telescope over a 0.84{deg}x6{deg} region centered near the Trapezium region of the Orion Nebula cluster. These data are used to establish the near-infrared variability properties of premain-sequence stars in Orion on timescales of ~1-36days, ~2 months, and ~2 years. A total of 1235 near-infrared variable stars are identified, ~93% of which are likely associated with the Orion A molecular cloud.