The study of small bodies that have a cometary activity at a large heliocentric distance (larger than 5AU) is important for a better understanding of the physical properties of comets and their origin. Such studies require long-term monitoring and a significant observational effort. Our goal is to monitor the cometary activity and search for possible emission lines of C/2006 S3 (LONEOS), which is a distant comet that was discovered in 2006 and passed perihelion at 5.13AU in April 2012.