To investigate how a large-scale infrared bubble centered at l=53.9{deg} and b=0.2{deg} forms, and to study if star formation is taking place at the periphery of the bubble, we performed a multiwavelength study. Using the data from the Galactic Ring Survey (GRS) and Galactic Legacy Infrared Mid-Plane Survey Extraordinaire (GLIMPSE), we performed a study of a large-scale infrared bubble with a size of about 16pc at a distance of 2.0kpc. We present the ^12^CO J=1-0, ^13^CO J=1-0, and C^18^O J=1-0 observations of HII region G53.54-0.01 (Sh2-82) obtained at the Purple Mountain Observation (PMO) 13.7m radio telescope to investigate the detailed distribution of associated molecular material. In addition, we also used radiorecombination line and VLA data. To select young stellar objects (YSOs) consistent with this region, we used the GLIMPSE I catalog.