The cluster 47 Tuc is among the most metal-rich Galactic globular clusters and its metallicity is similar to that of metal-poor disc stars and open clusters. Like other globular clusters, it displays variations in the abundances of elements lighter than Si, which is generally interpreted as evidence of the presence of multiple stellar populations. We aim to determine abundances of Li, O, and Na in a sample of of 110 turn-off (TO) stars, in order to study the evolution of light elements in this cluster and to put our results in perspective with observations of other globular and open clusters, as well as with field stars. We use medium resolution spectra obtained with the GIRAFFE spectrograph at the ESO 8.2m Kueyen VLT telescope and use state of the art 1D model atmospheres and NLTE line transfer to determine the abundances. We also employ CO^5^BOLD hydrodynamical simulations to assess the impact of stellar granulation on the line formation and inferred abundances.