Establishing the multiplicity of O-type stars is the first step towards accurately determining their stellar parameters. Moreover, the distribution of the orbital parameters provides observational clues to the way that O-type stars form and to the interactions during their evolution. Our objective is to constrain the multiplicity of a sample of O-type stars belonging to poorly investigated OB associations in the Cygnus complex and for the first time to provide orbital parameters for binaries identified in our sample. Such information is relevant to addressing the issue of the binarity in the context of O-type star formation scenarios.